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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NBEAL2 All Species: 12.73
Human Site: S1046 Identified Species: 25.45
UniProt: Q6ZNJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNJ1 NP_055990.1 2754 302517 S1046 L G H I Q Y M S S I V R E H R
Chimpanzee Pan troglodytes XP_525997 2750 313008 S1055 I G H I Q Y L S T I I K D S R
Rhesus Macaque Macaca mulatta XP_001094456 2295 260424 G681 V K A L Y L A G P N C L S P W
Dog Lupus familis XP_541900 2305 251162 R691 P G H G L D G R L T G H R V E
Cat Felis silvestris
Mouse Mus musculus Q6ZQA0 2742 301906 S1045 L G H I Q Y M S S M V R E H R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508701 2269 259447 C655 V L P E H S F C D S L W H N I
Chicken Gallus gallus XP_421964 2298 259902 T684 T K M I S A G T Q D S E W G C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4E2 3584 396477 S1197 D D V L Q E S S S V L K D E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19317 2507 281187 K879 G E R L L S H K K V L S L P T
Sea Urchin Strong. purpuratus XP_785921 3355 375569 A1689 I G H I Q Y L A T I I K D N R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182078 2946 321916 S1120 V T S N I L G S G L H E N G G
Baker's Yeast Sacchar. cerevisiae P25356 2167 250854 F553 L E F C G W D F N D I S K S I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.1 40.2 74.6 N.A. 88 N.A. N.A. 39.7 40.6 N.A. N.A. N.A. 20.7 N.A. 21.1 33.4
Protein Similarity: 100 65.6 56.3 77.1 N.A. 92 N.A. N.A. 53.8 55.7 N.A. N.A. N.A. 36.1 N.A. 37.4 48.8
P-Site Identity: 100 53.3 0 13.3 N.A. 93.3 N.A. N.A. 0 6.6 N.A. N.A. N.A. 20 N.A. 0 46.6
P-Site Similarity: 100 93.3 13.3 13.3 N.A. 100 N.A. N.A. 20 13.3 N.A. N.A. N.A. 53.3 N.A. 20 100
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 9 9 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 9 0 0 9 0 0 0 9 % C
% Asp: 9 9 0 0 0 9 9 0 9 17 0 0 25 0 0 % D
% Glu: 0 17 0 9 0 9 0 0 0 0 0 17 17 9 17 % E
% Phe: 0 0 9 0 0 0 9 9 0 0 0 0 0 0 0 % F
% Gly: 9 42 0 9 9 0 25 9 9 0 9 0 0 17 9 % G
% His: 0 0 42 0 9 0 9 0 0 0 9 9 9 17 0 % H
% Ile: 17 0 0 42 9 0 0 0 0 25 25 0 0 0 17 % I
% Lys: 0 17 0 0 0 0 0 9 9 0 0 25 9 0 0 % K
% Leu: 25 9 0 25 17 17 17 0 9 9 25 9 9 0 0 % L
% Met: 0 0 9 0 0 0 17 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 9 9 0 0 9 17 0 % N
% Pro: 9 0 9 0 0 0 0 0 9 0 0 0 0 17 0 % P
% Gln: 0 0 0 0 42 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 9 0 0 0 0 9 0 0 0 17 9 0 34 % R
% Ser: 0 0 9 0 9 17 9 42 25 9 9 17 9 17 0 % S
% Thr: 9 9 0 0 0 0 0 9 17 9 0 0 0 0 9 % T
% Val: 25 0 9 0 0 0 0 0 0 17 17 0 0 9 0 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 9 9 0 9 % W
% Tyr: 0 0 0 0 9 34 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _